September 7, 2026 · Fertility and sterility · DOI: 10.1016/j.fertnstert.2026.08.1133

PMOS beyond the reproductive years: menopause and long-term health outcomes

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The authors investigate how Polyendocrine Metabolic Ovarian Syndrome (PMOS) affects women's health beyond their reproductive years, particularly focusing on the long-term implications for metabolic dysfunction, cardiovascular disease, and psychological health. They highlight the challenges in diagnosing PMOS in older women due to symptom improvements that do not indicate resolution of the disorder, emphasizing the need for more longitudinal studies to better understand its lifelong impact. The review calls for increased awareness and multidisciplinary management of PMOS as a chronic condition throughout a woman's life.

Elena HogenEsch, Heather G Huddleston

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