Abnormal serum sFlt-1 and PlGF as markers of occult placental dysfunction and fetal risk in pregestational diabetes: A Prospective Masked Cohort Study
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The authors aimed to determine the prevalence of angiogenic biomarker abnormalities (sFlt-1 and PlGF) in pregnant individuals with pregestational diabetes and their association with adverse perinatal outcomes. They found that these biomarkers can predict complications such as preterm birth and preeclampsia, independent of fetal size, suggesting that routine measurement of these biomarkers could enhance fetal surveillance protocols.
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