Preconception 1-hour blood glucose as an early indicator of gestational diabetes mellitus risk in PMOS/PCOS women undergoing IVF treatment: a multi-centre cohort study

The study investigates whether preconception 1-hour plasma glucose levels during an oral glucose tolerance test (OGTT) are more predictive of gestational diabetes mellitus (GDM) compared to fasting or 2-hour glucose levels in women with PMOS/PCOS undergoing IVF treatment. The findings indicate that 1-hour glucose levels show a stronger and more consistent association with GDM risk, particularly in normal-weight and obese women, suggesting its potential value in preconception metabolic assessments for this population.