July 23, 2026 · Obstetrics and gynecology · DOI: 10.1097/AOG.0000000000006383

Vulvar Lichen Sclerosus

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The authors investigate vulvar lichen sclerosus (VLS), a T-cell-mediated inflammatory condition affecting 0.5-3% of women, characterized by symptoms such as itching and dyspareunia, and potential anatomic changes. They highlight the importance of early diagnosis and treatment, primarily with ultra-high-potency topical steroids, to mitigate the risk of malignancy and progression of anatomic changes, which may necessitate surgical intervention. The paper emphasizes the significant impact of VLS on patients' quality of life and the need for ongoing management, even in asymptomatic cases.

Adrienne Bonham

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