July 23, 2026 · Climacteric : the journal of the International Menopause Society · DOI: 10.1080/13697137.2026.2694475

Comparing aerobic and resistance training in estrogen deficiency: bone and muscle adaptations

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This study aimed to compare the effects of aerobic and resistance training on bone and muscle adaptations in ovariectomized mice, a model for estrogen deficiency. The results showed that both exercise modalities improved bone metabolism, but resistance training had more pronounced effects, including increased osteocyte density and muscle fiber size, suggesting it may be a more effective strategy for mitigating bone deterioration associated with menopause.

Pedro Gustavo Machado, Juliana Cristina Dos Reis Canaan, Luciana Botelho Ribeiro, José Victor Mauricio de Jesus, Heloisa Oliveira Dos Santos, Natália Oliveria Bertolini, Ivam Moreira de Oliveira Júnior, Wilson Vicente Souza Pereira, Eric Francelino Andrade, Luciano José Pereira

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