Beta-Blockers and Exercise Performance in Children with Long QT Syndrome
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This study aimed to investigate the impact of beta-blocker dosage on exercise performance, specifically cardiopulmonary fitness, in children with long QT syndrome (LQTS). The authors found no significant correlation between nadolol dosage and objective measures of exercise performance, such as peak oxygen consumption and respiratory exchange ratio, suggesting that beta-blocker treatment does not adversely affect exercise capacity in most patients with LQTS. These findings were further supported by data from a validation cohort using atenolol.
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