Physiological Markers of Effective Autonomic Denervation Are Associated With Outcomes After Cardioneuroablation for Vasovagal Syncope

The authors aimed to identify procedural markers associated with long-term outcomes following cardioneuroablation (CNA) for patients with recurrent vasovagal syncope. They found that specific physiological responses during the procedure, such as a vagal response and an increase in sinus rate, were linked to a lower recurrence of syncope, suggesting that these markers could help optimize CNA outcomes. Despite these findings, the study also highlighted a significant rate of recurrent syncope in the intermediate term, indicating the need for improved procedural endpoints.