Outcomes of Long-Term Antibiotic Therapy in Women with Chronic Recalcitrant Cystitis

The authors aimed to evaluate the effectiveness of long-term antibiotic therapy in improving patient-reported outcomes for women with chronic recalcitrant cystitis (CRC), a condition characterized by persistent lower urinary tract symptoms despite negative urine cultures. Their retrospective study found that 71.4% of participants adhered to the treatment, with significant improvements in urinary distress and pain coping reported after one year, suggesting that long-term antibiotics may benefit this patient population. However, the authors call for prospective studies to further clarify the role of antibiotics in managing CRC.