Technical evaluation of commercially available homologous recombination deficiency assays using MyChoice CDx as reference in ovarian cancer
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The authors aimed to evaluate the concordance of homologous recombination deficiency (HRD) status and associated biomarkers between the FDA-approved MyChoice® CDx and four commercially available assays in patients with platinum-sensitive relapsed ovarian cancer. Their findings demonstrated that these assays showed varying degrees of agreement with MyChoice CDx, suggesting their potential clinical utility in guiding treatment decisions for ovarian cancer. Overall, the study highlights the importance of reliable HRD detection for optimizing therapeutic strategies in this patient population.
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