Prehabilitation during neoadjuvant chemotherapy in advanced ovarian cancer is associated with improved surgical candidacy and chemotherapy outcomes
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The authors aimed to evaluate the impact of a structured multimodal prehabilitation program during neoadjuvant chemotherapy (NACT) on chemotherapy delivery, treatment tolerability, and surgical candidacy in patients with advanced-stage ovarian cancer. Their findings indicate that prehabilitation is associated with improved relative dose intensity of chemotherapy and a lower failure rate to proceed to interval debulking surgery, particularly in patients aged 70 and older. These results suggest that prehabilitation may enhance treatment adherence and outcomes in advanced ovarian cancer.
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