June 21, 2026 · American journal of ophthalmology · DOI: 10.1016/j.ajo.2026.06.023

Association between 24-Hour Blood Pressure and Rates of Retinal Nerve Fiber Layer Progression in Glaucoma: The Vascular Imaging in Glaucoma Study

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The authors aimed to investigate the relationship between 24-hour blood pressure (BP) and the rate of retinal nerve fiber layer (RNFL) loss in patients with primary open-angle glaucoma (POAG). Their findings indicate that lower systemic BP, particularly minimum mean arterial pressure (MAP), systolic BP, and diastolic BP, is associated with accelerated RNFL loss, suggesting that 24-hour BP monitoring could be a valuable tool for identifying glaucoma patients at higher risk of progression.

Davis B Zhou, Alessandro A Jammal, Richard Donkor, David S Greenfield

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