June 24, 2026 · American journal of ophthalmology · DOI: 10.1016/j.ajo.2026.06.038

The Impact of PCSK9 Inhibitors on Development of Retinal Vascular Occlusions

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This study investigates the relationship between the use of PCSK9 inhibitors (PCSK9i) and the risk of developing retinal vascular occlusions in patients with hyperlipidemia. The authors found that patients prescribed PCSK9i had a significantly lower risk of retinal artery and vein occlusions over a seven-year period compared to those on other lipid-lowering medications, suggesting that PCSK9i may offer protective microvascular effects.

Isabella H Yazji, Nadia J Abbass, David C Kaelber, Katherine E Talcott, Rishi P Singh

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