Association between statin use and dry eye disease: A systematic review and meta-analysis
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This systematic review and meta-analysis aimed to clarify the association between statin use and dry eye disease (DED), given mixed evidence from individual studies. The analysis of six observational studies involving over 560,000 participants found a statistically significant association, indicating that statin users had a 10.2 additional cases of DED per 1,000 individuals, although the evidence was of very low certainty. The authors recommend that healthcare providers monitor ocular surface symptoms in patients on statins, especially those with pre-existing DED risk factors.
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