Combined bladder-kidney transplantation: first-in-human feasibility trial

The authors investigate the feasibility and safety of combined bladder-kidney transplantation as a novel treatment for patients with terminal bladder dysfunction and end-stage kidney disease. The first-in-human trial demonstrated successful surgical outcomes, with the patient maintaining good renal and bladder function, sensation, and continence beyond six months post-transplantation, suggesting this approach may be a viable option for select patients requiring immunosuppression.