June 19, 2026 · American journal of ophthalmology · DOI: 10.1016/j.ajo.2026.06.022

Association of the Charlson Comorbidity Index with one-year outcomes in patients with macular edema secondary to retinal vein occlusion

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The authors aimed to assess the predictive value of the Charlson Comorbidity Index (CCI) on visual and anatomical outcomes in patients with macular edema secondary to retinal vein occlusion (RVO). Their findings indicate that higher CCI scores correlate with poorer best-corrected visual acuity outcomes, particularly in patients with more comorbidities, while baseline central subfield thickness was a stronger predictor of final thickness outcomes across all comorbidity levels.

Jonathan J Xavier, J Hayden A Reed, Kanisha S Bahierathan, Sonia B Kim, Katherine E Talcott, Rishi P Singh

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