Real-world effectiveness of mono- and combination therapies of mood stabilisers and antipsychotics in bipolar disorder: nationwide, within-individual study of 315 046 patients
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The authors aimed to assess the effectiveness of mono- and combination therapies involving mood stabilisers and antipsychotics in preventing psychiatric hospitalisation among patients with bipolar disorder. Utilizing a large population-based cohort study of over 315,000 patients, they found that both monotherapy and combination therapy significantly reduced the risk of hospitalisation compared to non-use of these medications. The results indicate that treatment strategies can be optimized based on the varying effectiveness of these pharmacotherapies in clinical practice.
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