Psychiatry & Neurology
Audio Summaries

Deltoid Osteomuscular Transfer Suppresses Humeral Head Translation Caused by Massive Irreparable Rotator Cuff Tears: A Cadaveric Biomechanical Study

The authors aimed to evaluate the biomechanical effectiveness of a modified deltoid flap transfer, termed deltoid osteomuscular transfer (DOT), in managing massive irreparable rotator cuff tears (MRCTs) using a cadaveric model. Their findings demonstrated that the anterior harvest DOT significantly reduced humeral head translation compared to MRCT under various conditions and improved functional abduction force, suggesting it may provide effective stabilization for patients with irreparable MRCTs.

Lateral Extra-articular Tenodesis Restores Knee Rotational and Translational Stability Regardless of Fixation Type: A Matched-Pair Cadaveric Study

The authors aimed to compare the biomechanical stability of the knee using three different fixation methods for lateral extra-articular tenodesis (LET) during anterior cruciate ligament reconstruction. Their findings indicated that all fixation methods—suture anchors, interference screws, and metallic staples—restored knee rotational stability effectively, even after cyclic loading, although suture anchors showed greater vulnerability to cyclic stress compared to the other methods. Ultimately, all three fixation techniques are considered viable options for LET, with no significant differences in overall stability observed between them in a controlled laboratory setting.

Economic and Regional Disparities in Critical Care Ultrasound Training, Equipment Access, and Implementation Barriers in China: A Nationwide Cross-Sectional Survey

The authors aimed to evaluate the utilization, training, and barriers to critical care ultrasound (CCUS) among ICU clinicians across economically diverse regions in China. They found that while training coverage was similar in high- and low-GDP areas, significant disparities existed in self-assessed proficiency and equipment availability, with major barriers including insufficient expert support and challenges in image interpretation. The study concludes that structured training can enhance CCUS usage and expertise, highlighting the need for policies that promote equitable access to training and resources across all regions.

Clinical Outcomes of Unipolar Versus Bipolar Patellofemoral Fresh Osteochondral Allograft Transplantation

The authors aimed to compare the clinical outcomes, including graft failure rates, reoperation rates, and patient-reported outcomes (PROs), between unipolar and bipolar patellofemoral osteochondral allograft (OCA) transplantation after a minimum follow-up of two years. Their findings indicated that while bipolar lesions were associated with a higher risk of graft failure, both unipolar and bipolar transplantations resulted in similar improvements in PROs and comparable reoperation rates, suggesting that both techniques are effective for patients in this cohort.

Tibiofemoral Load Sharing and Lateral Meniscal Function Are Restored in Tibia- and Capsular-Based Repair of Type 3 Lateral Meniscal Oblique Radial Tears

The authors investigate how type 3 lateral meniscal oblique radial tears (LMORTs) affect tibiofemoral contact mechanics and meniscal function, and whether different repair techniques can restore these metrics to their native levels. They found that both tibia-based suture anchor and capsular-based side-to-side repairs effectively restored joint mechanics and meniscal function, while debridement yielded poorer outcomes. This study supports the biomechanical rationale for repairing type 3 LMORTs during anterior cruciate ligament reconstruction.

A Placebo-Controlled Trial of the Oral PCSK9 Inhibitor Enlicitide

This study aimed to evaluate the efficacy of the oral PCSK9 inhibitor enlicitide in reducing LDL cholesterol levels in adults with a history of atherosclerotic cardiovascular disease or at risk for such events. The results demonstrated that enlicitide significantly lowered LDL cholesterol levels compared to placebo at both 24 and 52 weeks, with no notable difference in adverse events between the groups.

Impact of physical activity patterns on major adverse cardiovascular events in adults with hypertension

The authors aimed to investigate the relationship between physical activity (PA) patterns, specifically intensity and bout length, and the risk of major adverse cardiovascular events (MACEs) in adults with hypertension. Their findings indicate that both short and long bouts of moderate intensity PA are linked to a reduced risk of MACEs, while short bouts of vigorous intensity PA also show protective effects; however, longer bouts of vigorous activity are associated with a significantly increased risk of stroke. This study underscores the importance of considering both the intensity and duration of physical activity in managing cardiovascular health among hypertensive individuals.

A Case of 7-Hydroxymitragynine Use Disorder Treated With Buprenorphine

The authors investigate the management of 7-hydroxymitragynine (7-HMG) use disorder, a condition that is becoming more prevalent due to the increasing availability of this potent opioid. They present a case of a man treated successfully with a combination of methadone and buprenorphine, highlighting the need for further research on 7-HMG's effects and treatment strategies. The study underscores the potential for medication-assisted treatment in addressing 7-HMG addiction.

Stimulant-induced Psychosis: A Comparative Systematic Review and Meta-analysis of Psychotic Outcomes from Therapeutic and Nontherapeutic Use of Stimulants

The authors aimed to compare the incidence and prevalence of stimulant-induced psychosis between therapeutic (prescribed) and nontherapeutic (illicit or misused) stimulant use. Their systematic review and meta-analysis of 77 studies revealed a significantly lower incidence of psychosis in therapeutic users (0.6%) compared to a high prevalence in nontherapeutic users (32.8%), highlighting the need for careful monitoring and harm-reduction strategies in nonmedical contexts. The findings suggest that while prescribed stimulants carry a low risk, nontherapeutic use poses a substantial public health concern due to the severity and recurrence of psychotic symptoms.

Evaluating Clinicians' Perspectives on Initiation of Medications for Opioid Use Disorder During Psychiatric Admissions

The authors aimed to evaluate clinicians' perspectives on the initiation of medications for opioid use disorder (MOUD) during psychiatric admissions, given the high prevalence of opioid use disorder among this population. Through semistructured interviews with clinical staff, they identified themes related to the acceptance of opioid withdrawal treatment, misconceptions about MOUD, and the impact of stigma, ultimately advocating for improved education and a multidisciplinary approach to enhance MOUD implementation in psychiatric settings.