CIMT as a sensitive indicator of cardiovascular risk in PCOS: a case-control study of sortilin and sclerostin
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This study investigates the role of serum sortilin and sclerostin levels, along with carotid intima-media thickness (CIMT) and pulse wave velocity (PWV), in assessing cardiovascular risk among women with polycystic ovary syndrome (PCOS) compared to controls. The findings indicate that CIMT is significantly elevated in women with PCOS, while sortilin and sclerostin levels do not differ between groups and are not independently associated with CIMT. The authors conclude that CIMT is a more effective marker for early subclinical atherosclerosis in this population than the studied biomarkers, highlighting the need for further research to explore their potential relevance in specific subgroups.
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