February 18, 2026 · BMC women's health · DOI: 10.1186/s12905-026-04348-8

Central sensitization in women with endometriosis: a cross-sectional study

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This study aimed to assess the prevalence of central sensitization in women diagnosed with endometriosis or adenomyosis and to explore its association with various demographic and clinical characteristics. The findings revealed a high prevalence of central sensitization (52.1%) among the participants, with significant links to dyspareunia, vulvodynia, and symptom onset after five years. The authors suggest that early identification of central sensitization could enhance patient counseling and inform multimodal treatment strategies.

Anna Biasioli, Francesca Previtera, Ilaria Mazzera, Matilde Degano, Silvia Zermano, Veronica Tius, Ilaria Piacenti, Renato Seracchioli, Diego Raimondo, Monica Della Martina, Martina Arcieri, Stefano Restaino, Lorenza Driul, Giuseppe Vizzielli

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