January 30, 2026 · Reproductive biology and endocrinology : RB&E · DOI: 10.1186/s12958-026-01530-3

Association of metal exposure in follicular fluid with assisted reproductive technology outcomes in East Chinese women

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This study investigates the relationship between metal exposure in follicular fluid and the outcomes of assisted reproductive technology (ART) in East Chinese women. The authors found that higher levels of zinc and iron were associated with better embryo quality, while elevated calcium and copper levels correlated with lower oocyte maturation rates, and lead exposure negatively impacted embryo quality and clinical pregnancy outcomes. The results highlight the need for further research to understand the biological mechanisms linking metal exposure to female fertility.

Yao Han, Zongwei Guo, Di Yuan, Pengyun Qiao, Fa Ren

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