Eating disorders.

This Lancet review examines eating and feeding disorders, which are serious psychiatric conditions with high burdens on patients, families, and society, and asks where current knowledge and treatment fall short. The authors note that psychological therapies remain first-line with medications as adjuncts, that anorexia nervosa poses a difficult mix of high medical risk and treatment ambivalence, and that research funding lags well behind other psychiatric disorders. They conclude that progress will most likely come from longitudinal multimodal studies, big-data mechanistic research, and flexible trial designs aimed at more personalised interventions.