September 22, 2026 · Obstetrics and gynecology · DOI: 10.1097/AOG.0000000000006432

Effectiveness of Laparoscopic Radiofrequency Ablation of Uterine Leiomyomas Compared With Myomectomy on Symptoms and Health-Related Quality of Life

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The authors aimed to compare the effectiveness of laparoscopic radiofrequency ablation (RFA) and myomectomy in improving symptom severity and health-related quality of life (HRQOL) in women with symptomatic uterine leiomyomas. The study found that both treatments led to significant improvements over a 24-month period, but myomectomy resulted in slightly greater reductions in symptom severity and HRQOL, although these differences were not clinically significant. Overall, both interventions effectively alleviated symptoms and enhanced quality of life without substantial differences in outcomes.

Antoinette Allen, Michael Schembri, Ram Parvataneni, L Elaine Waetjen, Shira Varon, Naghmeh Salamat-Saberi, Henry Garza, Kimberly A Kho, Craig J Sobolewski, Soyini Hawkins, Nicole Williams, Shawn Tassone, Vanessa L Jacoby

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