September 9, 2026 · Chest · DOI: 10.1016/j.chest.2026.03.037

A 40-Year-Old Woman With Exertional Dyspnea and Unexplained Hypoxia

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The authors present a case of a 40-year-old woman with a history of stage IV lung adenocarcinoma who developed progressive exertional dyspnea and unexplained hypoxia, raising the question of the underlying causes of her respiratory symptoms despite stable disease status. The case highlights the complexities of managing patients with advanced cancer and the need to investigate potential non-tumor-related factors contributing to respiratory distress.

Yao-Dan Liang, Wei-Qing Meng, Yu-Xia Wang, Tao Gu, Xue-Feng Zhong, Li-Song Qiao, Xiao-Mao Xu

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