September 8, 2026 · Journal of cardiac failure · DOI: 10.1016/j.cardfail.2026.06.017

Beyond Tacrolimus: Toward Personalized Immunosuppression in Heart Transplantation

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The authors investigate the potential for personalized immunosuppression in heart transplantation, addressing the limitations of current regimens that lack individualization despite variability in recipient characteristics. They explore advancements in immune monitoring and biomarkers, propose a framework for integrating these tools into patient management, and suggest future directions, including innovative technologies and trial designs needed to enhance personalized approaches in this field.

Marc D Samsky, Maryjane A Farr, Aditya G Parikh, Yasbanoo Moayedi, Anat R Tambur, Palak Shah

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