September 8, 2026 · Journal of cardiac failure · DOI: 10.1016/j.cardfail.2026.06.026

The Future of Donor Heart Preservation

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The authors investigate advancements in donor heart preservation technologies aimed at expanding the donor pool and improving graft viability. They discuss various methods, including controlled hypothermia, normothermic ex vivo perfusion, and hypothermic oxygenated perfusion, highlighting their potential to enhance preservation times and reduce organ injury. Ultimately, the paper explores how these innovations could increase access to heart transplantation by allowing for the use of extended-criteria and donation after circulatory death donors.

Sameer K Singh, Koji Takeda

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