September 1, 2026 · The New England journal of medicine · DOI: 10.1056/NEJMoa2608012

Catheter-Directed Thrombolysis in Intermediate-High-Risk Pulmonary Embolism

Listen to this summary

The authors aimed to determine whether catheter-directed thrombolysis with alteplase improves clinical outcomes compared to anticoagulation alone in patients with intermediate-high-risk pulmonary embolism. Their findings indicated that the thrombolysis group experienced significantly fewer primary outcome events, including death, recurrent pulmonary embolism, and cardiorespiratory decompensation, within 7 days after treatment, suggesting a beneficial effect of thrombolysis in this patient population.

Josef Kroupa, Martin Radvan, Jan Mrozek, Martin Sluka, Stepan Jirous, Ota Hlinomaz, Milan Pliva, Jan Pudil, Hana Voberkova, Karolina Bartoskova, Martin Poloczek, Martin Kamenik, Michal Brabec, Eva Lichnerova, Martin Hutyra, Ivo Bernat, Martin Novak, Johana Horakova, Lucie Jelinkova, Tomas Knize, Petr Tousek, Cyril Stechovsky, Filip Varhanik, Zdenek Coufal, Jiri Jarkovsky, Viktor Kocka

This is one of 33,000+ journals available on OSLR. Try it free for 14 days.

Free 14-day trial. 33,000+ journals. Cancel anytime.

14-day free trial. No commitment.

More in Obstetrics & Gynecology

View all →

Sep 3, 2026 · International urogynecology journal

Robotic-Assisted Early Repair of Vesicovaginal Fistula in a Colon Cancer Patient: A Case Report and Surgical Technique Video

Sep 3, 2026 · Obstetrics and gynecology

The Cardiometabolic Effects of Menopause

Sep 3, 2026 · BMC women's health

Psychometric properties of the Chinese version of the Meno-D in perimenopausal women

Sep 3, 2026 · BJOG : an international journal of obstetrics and gynaecology

Pre-Procedure Predictors of Six-Month Survival After Fetoscopic Laser Ablation for Twin-Twin Transfusion Syndrome (TTTS): Retrospective Observational Study

Sep 2, 2026 · Journal of lower genital tract disease

Heterogeneity in Risk of Recurrent CIN2+ Among Women With Genotype-Specific HPV Detected After Excision: A Cohort Study

Sep 2, 2026 · International urogynecology journal

Obstetric Factors Associated with Pelvic Floor Disorders and Surgery 30 Years After Childbirth: A Prospective Cohort Study

“

"Oslr has become part of my weekly routine on my day off. The clinical relevance of the summaries is outstanding — I'd rate it 9/10. Being able to consume research hands-free is a huge advantage for busy physicians."

Dr. Jennifer Thompson

Portland, OR

Stay current without falling behind

33,000+ journals. 3-minute audio summaries. Free for 14 days.

Catheter-Directed Thrombolysis in Intermediate-High-Risk Pulmonary Embolism

More from The New England journal of medicine

Pulmonary Nodules

Daraxonrasib for Previously Treated <em>RAS</em>-Mutant Non-Small-Cell Lung Cancer

Milvexian with Antiplatelet Therapy after Acute Coronary Syndrome Event

Pulmonary Denervation for Heart Failure-Related Pulmonary Hypertension

Aspirin Omission at the Time of Primary Percutaneous Coronary Intervention in STEMI

Targeted Use of Computed Tomographic Coronary Angiography in Acute Chest Pain