August 31, 2026 · The New England journal of medicine · DOI: 10.1056/NEJMoa2608903

Targeted Use of Computed Tomographic Coronary Angiography in Acute Chest Pain

Listen to this summary

This study aimed to determine whether targeted use of computed tomographic coronary angiography (CTCA) in patients with suspected acute coronary syndrome, after ruling out myocardial infarction, could reduce the risk of subsequent myocardial infarction or cardiac death compared to standard care. The results showed no significant difference in the incidence of these outcomes between the CTCA-guided management group and the standard care group after a median follow-up of 3 years. Thus, routine CTCA did not provide a benefit in this patient population.

Kuan Ken Lee, Ryan Wereski, David Lowe, Rachel O'Brien, Amy V Ferry, Anda Bularga, Matthew T H Lowry, Caelan Taggart, Giles Roditi, Nick Curzen, Sarojini David, Dirk Felmeden, Randeep Hunjan, Attila Kardos, Liza Keating, Dennis Sandeman, Jason E Smith, Carl Roobottom, Chris Tuck, Denise Cranley, Praveen Thokala, Steve Goodacre, Titouan Kennel, Catriona Keerie, John Norrie, Michelle C Williams, David E Newby, Alasdair J Gray, Nicholas L Mills, TARGET-CTCA Investigators

This is one of 33,000+ journals available on OSLR. Try it free for 14 days.

Free 14-day trial. 33,000+ journals. Cancel anytime.

14-day free trial. No commitment.

"Oslr has become part of my weekly routine on my day off. The clinical relevance of the summaries is outstanding — I'd rate it 9/10. Being able to consume research hands-free is a huge advantage for busy physicians."

Dr. Jennifer Thompson

Dr. Jennifer Thompson

Portland, OR

Stay current without falling behind

33,000+ journals. 3-minute audio summaries. Free for 14 days.

Download on the App StoreGet it on Google Play