From Rescue to Interception: The PREVENT 2-LATE Framework for Advanced Heart Failure

The authors aim to address the challenge of timely referral for advanced heart failure therapies by proposing the PREVENT 2-LATE framework, which identifies patients earlier in their disease trajectory using specific clinical signals. This framework emphasizes a multidisciplinary approach to proactively manage patients before they reach critical stages, thereby preserving treatment options and improving long-term outcomes. Additionally, the paper consolidates best practices for left ventricular assist device (LVAD) management to enhance clinician confidence and optimize patient care.