Preoperative prebiotic supplementation alleviates colitis and improves anastomotic healing associated with modulation of the gut microbiota in rats
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The authors investigate whether preoperative prebiotic supplementation can alleviate colitis and enhance anastomotic healing in a rat model, particularly in the context of bacterial dysbiosis associated with inflammatory bowel disease. Their findings suggest that a complex prebiotic supplement improves microbial diversity, protects against colitis-related damage, and strengthens anastomotic integrity, indicating its potential role in microbiota-targeted prehabilitation for colorectal surgery patients.
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