Health-related quality of life in children with chronic kidney disease: clinical predictors and ROC-derived thresholds for impaired HRQoL
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This study investigates the health-related quality of life (HRQoL) in children with chronic kidney disease (CKD) and aims to identify clinical predictors of impaired HRQoL. The authors found that children with CKD had significantly lower HRQoL compared to healthy controls, with specific renal function parameters like eGFR and BUN being associated with poorer HRQoL. They established a clinically interpretable cutoff score for HRQoL impairment and suggest that integrating HRQoL assessments into pediatric nephrology could improve patient-centered care.
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