August 7, 2026 · European heart journal · DOI: 10.1093/eurheartj/ehag577

Temporal comparison of clinical practice and outcomes in heart failure: the JROADHF and JROADHF-NEXT studies

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This study aimed to evaluate the temporal changes in heart failure (HF) management and their impact on patient outcomes by comparing two large-scale Japanese HF registries from 2013 and 2019-21. The findings revealed significant improvements in guideline-recommended therapies and a marked reduction in one-year mortality and HF readmission rates, suggesting that advancements in pharmacotherapy and post-discharge care have positively influenced long-term outcomes for HF patients.

Takeshi Tohyama, Masataka Ikeda, Tatsuya Watanabe, Nobuyuki Enzan, Hidetaka Kaku, Eri Noda, Takuya Nagata, Yoshitomo Tsutsui, Shouji Matsushima, Yuya Matsue, Keisuke Kida, Takeshi Kitai, Tatsunori Taniguchi, Takahiro Okumura, Koshiro Kanaoka, Yoko Sumita, Yoshihiro Miyamoto, Kohtaro Abe, Hiroyuki Tsutsui, Tomomi Ide

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