Efficacy and Safety of Radiofrequency as a Treatment Modality for Genitourinary Syndrome of Menopause: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

The authors aimed to evaluate the efficacy and safety of radiofrequency (RF) therapy for managing genitourinary syndrome of menopause (GSM) compared to other treatment modalities. Their systematic review and meta-analysis of eight randomized controlled trials found that RF therapy significantly improved sexual function compared to vaginal estrogen and placebo/moisturizer, while showing comparable results to laser therapy. Additionally, RF therapy was associated with mild adverse events, indicating a favorable safety profile.