July 27, 2026 · JAMA internal medicine · DOI: 10.1001/jamainternmed.2026.2879

An Indigenous Food Is Medicine Intervention: The MUTTON-HF Randomized Clinical Trial

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The authors aimed to evaluate the efficacy of a culturally and medically tailored meal program, incorporating traditional Navajo foods, on reducing hospitalizations and emergency department visits among adults with heart failure. The randomized clinical trial found that participants in the intervention group experienced significantly fewer hospitalizations and improved quality of life measures compared to those receiving usual dietary advice. These findings suggest that community-based interventions utilizing traditional foods can enhance health outcomes in Indigenous populations.

Lauren A Eberly, Carmen George, Sharon Sandman, Denee Bex, Karianne Jones, Asia Yazzie, Leah Gray, Larissa Morgan, Ada Tennison, Conor Williams, Matt Chandra, Rebecca Wickre, Bennett Wickre, Mackenzie Bolas, Remi Welbel, Delaney Ignace, Benjamin Feliciano, Stacy Hammer, DezBaa Damon-Mallette, Erica Lindsey, Paula Mora, Aijun Ye, Maricruz Merino, Enrique F Schisterman, Sonya S Shin

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