Pediatric sepsis-associated acute kidney injury: leveraging pathophysiology for risk stratification and identification of treatable traits
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The authors aim to explore the complex pathophysiology of sepsis-associated acute kidney injury (SA-AKI) in pediatric patients to enhance risk stratification and identify treatable traits. They emphasize the need for a precision medicine approach that utilizes phenotypes and biomarkers to better predict outcomes and optimize therapies for affected children. The review highlights current knowledge and clinical tools relevant to SA-AKI in pediatrics, advocating for actionable strategies based on mechanistic insights.
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