Rationale and Design of the TAILOR-HCM Multicenter Randomized Controlled Trial: Transapical Beating-Heart Septal Myectomy for Obstructive Hypertrophic Cardiomyopathy
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The TAILOR-HCM trial aims to evaluate the safety and efficacy of transapical beating-heart septal myectomy (TA-BSM) compared to conventional septal myectomy (CSM) in patients with obstructive hypertrophic cardiomyopathy (oHCM). This multicenter, randomized controlled trial will assess whether TA-BSM can achieve similar clinical outcomes as CSM, particularly in relieving left ventricular outflow tract obstruction, while also examining safety outcomes and quality of life. The findings could potentially expand treatment options for patients with oHCM by providing evidence for a less complex surgical approach.
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