July 15, 2026 · Paediatric anaesthesia · DOI: 10.1002/pan.70267

Comparison of Discharge Readiness in Pediatric Patients: Oral Versus Intranasal Preoperative Midazolam Administration

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The authors aimed to compare the effects of oral versus intranasal midazolam on discharge readiness in pediatric patients undergoing tympanostomy, specifically examining the length of stay in the post-anesthesia care unit (PACU). Their findings indicated that while intranasal midazolam initially appeared to result in a shorter PACU stay, this difference was confounded by the younger age of patients receiving this route, with age being the primary predictor of PACU length of stay. The study suggests that previous observations of recovery time differences may be influenced more by age than by the route of midazolam administration, highlighting the need for further research to clarify these relationships.

Mohammad Naem, Jobayer Hossain, Janna Hamideh, Judit Szolnoki

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