August 1, 2026 · Paediatric anaesthesia · DOI: 10.1002/pan.70275

Evaluating the Impact of Clonidine and Midazolam Premedication on Emergence Delirium in Pediatric Patients

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This study aimed to evaluate the impact of premedication with clonidine or midazolam on the incidence of emergence delirium in pediatric patients undergoing general anesthesia. The analysis of data from 4,796 anesthetics revealed a low overall incidence of emergence delirium, with no significant association found for clonidine, while midazolam appeared to be linked to an increased risk.

Anne Louise de Barros Garioud, Anwen Taplin, Yufei Shang, R Nazim Khan, David Sommerfield, Neil Hauser, Aine Sommerfield, Britta S von Ungern-Sternberg

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