Effects of Esketamine on Emergence Delirium in Children Undergoing Sevoflurane Anesthesia: A Systematic Review, Meta-Analysis, and Trial Sequential Analysis
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This systematic review and meta-analysis aimed to evaluate the efficacy and safety of esketamine in preventing emergence delirium in children undergoing sevoflurane anesthesia. The findings indicate that esketamine significantly reduces the incidence of emergence delirium and postoperative pain, while also decreasing postoperative nausea and vomiting, although it is associated with a modest increase in extubation time. Overall, the evidence suggests that esketamine is a promising option for improving postoperative outcomes in pediatric patients.
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