Reno-ocular syndromes: pathophysiological mechanisms linking kidney and ocular disorders
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This review article investigates the shared genetic and molecular mechanisms linking renal and ocular disorders, highlighting the interdependence of kidney and eye development. The authors explore how pathways such as BMP-7 and PAX2, along with extracellular matrix components, contribute to the pathophysiology of various syndromes and diseases affecting both organs. Additionally, they discuss the implications of these connections for diagnostics and the potential use of retinal imaging as a non-invasive tool for assessing kidney health.
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