Modification effect of multiple gestation on the relationship between maternal body mass index and miscarriage in frozen-thawed embryo transfer: a retrospective cohort study
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This study investigates how pregnancy plurality (singleton vs. twin) modifies the relationship between maternal body mass index (BMI) and miscarriage risk following frozen-thawed embryo transfer (FET). The findings indicate that elevated maternal BMI significantly increases the risk of miscarriage, with this association being stronger in twin pregnancies compared to singletons. The authors emphasize the importance of preconception weight management and suggest considering elective single embryo transfer for overweight and obese patients to mitigate miscarriage risks.
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