July 2, 2026 · Gynecologic oncology reports · DOI: 10.1016/j.gore.2026.102150

Management and sequelae of a local skene's gland adenocarcinoma recurrence

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The authors aim to address the management challenges and outcomes associated with recurrent Skene's gland adenocarcinoma, a rare malignancy with complex diagnostic features. They present a case of a 62-year-old woman who experienced local recurrence after initial treatment, ultimately requiring extensive surgical intervention following complications from prior radiation therapy. This case highlights the importance of multidisciplinary approaches in managing such rare periurethral cancers, particularly in previously irradiated patients.

Naziba Nuha, Katherine Trymbulak, Martin King, Benjamin Margolis

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