June 22, 2026 · Circulation · DOI: 10.1161/CIRCULATIONAHA.125.077491

Challenges and Future Trends in Large Vessel Vasculitis

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The authors aim to address the challenges and future trends in the diagnosis and management of large vessel vasculitis (LVV), specifically giant cell arteritis and Takayasu arteritis. They highlight the complexities of LVV's pathogenesis, the difficulties in diagnosis due to nonspecific symptoms, and the need for advanced imaging and targeted therapies to improve patient outcomes. The review seeks to enhance understanding of LVV's mechanisms and management strategies, particularly regarding cardiovascular complications associated with the disease and its treatment.

Maria Sandovici, Kornelis S M van der Geest, Rosanne D Reitsema, Neeraj Dhaun, Taryn Youngstein, Alexandre Wagner Silva de Souza, Peter C Grayson, Berit D Nielsen, Marc R Dweck, Ellen Hendrikse, Andor W J M Glaudemans, Elisabeth Brouwer, Riemer H J A Slart

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