June 26, 2026 · Regional anesthesia and pain medicine · DOI: 10.1136/rapm-2026-107899

Sensory innervation of the knee joint: a narrative review of articular branch mapping and sensory receptor distribution

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This narrative review aims to clarify the distribution of sensory receptors and the articular branches involved in the innervation of the knee joint to enhance pain management strategies for knee conditions. The authors found significant spatial heterogeneity in nociceptor distribution, with the anterior capsule having the highest density, and identified key contributions from various nerves, including the femoral and sciatic nerves. These insights provide a foundational understanding for developing targeted analgesic interventions.

Hugo Zimmermann, Thomas Botrel, Cyril Quemeneur, Sébastien Bloc, Pierre Laumonerie

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