New persistent opioid use following surgery among opioid-naïve patients in the USA: a systematic review and meta-analysis of observational studies
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The authors conducted a systematic review and meta-analysis to estimate the pooled incidence of new persistent opioid use (NPOU) following surgery among opioid-naïve patients in the USA, as well as to examine its association with various risk factors and patient characteristics. They found that the pooled incidence of NPOU was 7.15%, with significant variability among studies, and highlighted the urgent need for effective non-opioid pain management strategies due to the potential risks associated with persistent opioid use.
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