June 23, 2026 · Journal of minimally invasive gynecology · DOI: 10.1016/j.jmig.2026.06.018

Visually Directed Hysteroscopic Biopsy in the Evaluation of Abnormal Uterine Bleeding and Postmenopausal Bleeding: A Joint Society Practice Guideline

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The authors aimed to provide evidence-based recommendations for the histopathologic evaluation of patients with abnormal uterine bleeding (AUB) and postmenopausal bleeding (PMB) by comparing the diagnostic accuracy of hysteroscopy versus blind endometrial biopsy. Their findings indicate that hysteroscopy, particularly when combined with biopsy, offers superior diagnostic accuracy for detecting various intrauterine pathologies, including endometrial cancer and hyperplasia, and should be integrated into diagnostic protocols for AUB and PMB. The guideline emphasizes the importance of visually directed biopsy to enhance diagnostic outcomes in these patients.

Joint Society Practice Guideline from AAGL-ESGE-GCH

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