June 18, 2026 · Journal of minimally invasive gynecology · DOI: 10.1016/j.jmig.2026.06.016

Ovarian tissue transplantation using autologous platelet-rich plasma: step-by-step surgical technique

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The authors aim to demonstrate a step-by-step surgical technique for ovarian tissue transplantation (OTT) using autologous platelet-rich plasma (PRP) to enhance graft efficiency and longevity, addressing the issue of follicular loss post-reimplantation. They report a successful case involving a 38-year-old woman, where the procedure restored endocrine function and resumed menstrual cycles within three months without hormonal replacement. A phase-II trial is currently underway to further evaluate the long-term effects of PRP on reproductive outcomes following OTT.

Stefano Ferla, Rossella Vicenti, Marisol Doglioli, Diego Raimondo

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