Journal of minimally invasive gynecology
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Risk, prevalence and survival outcomes of ovarian cancer in women with endometriosis: the ENDOCANCER systematic review and meta-analysis

May 8, 2026

This systematic review and meta-analysis aimed to clarify the relationship between endometriosis and the risk of developing epithelial ovarian cancer (EOC), as well as to assess survival outcomes in affected women. The findings indicate that while endometriosis significantly increases the relative risk of ovarian cancer, the absolute risk remains low, and patients with endometriosis-associated ovarian cancer (EAOC) tend to have better survival rates and distinct clinicopathologic features compared to those with non-EAOC. The authors advocate for personalized risk counseling and the development of phenotype-based stratification methods.

Three-Year Changes in Health-Related Quality of Life After Laparoscopic Hysterectomy: A Registry-Based Cohort Study

May 4, 2026

The study aimed to evaluate changes in health-related quality of life (HRQoL) three years after laparoscopic hysterectomy (LH) for various indications and to identify baseline factors influencing these changes. Results indicated significant improvements in HRQoL for women undergoing LH for benign conditions, while those with prophylactic surgery showed no significant changes, and women with malignant indications experienced mixed outcomes. The authors found that higher baseline HRQoL was a strong predictor of less improvement over time, emphasizing its importance in preoperative counseling.

Bridging the Gap Between Artificial Intelligence and Clinical Readiness in Endometriosis Diagnosis: A Systematic Review

May 2, 2026

The authors aim to systematically evaluate the methodological quality and diagnostic performance of artificial intelligence applications in diagnosing endometriosis through imaging and clinical symptoms. Their review finds that while AI models show promising diagnostic accuracies, significant limitations exist, including clinical heterogeneity and biases in study populations, which hinder their readiness for clinical application. They emphasize the need for future research to focus on prospective validation in diverse patient groups to enhance the clinical utility of these AI tools.

Comments on "Understanding the Value of the Uterus: A Nationwide Cross-sectional Survey on Women's Preferences with Benign Gynecological Conditions"

May 2, 2026

The authors provide commentary on a nationwide cross-sectional survey that investigates women's preferences regarding the uterus in the context of benign gynecological conditions. They aim to highlight the significance of understanding women's perspectives on uterine health and treatment options, which can inform clinical practices and patient-centered care.

Bowel Injuries Reported After NovaSure® Endometrial Ablation: A 10-Year Review of FDA MAUDE Data

Apr 26, 2026

The authors aimed to characterize adverse events related to bowel injuries associated with NovaSure® endometrial ablation devices by analyzing data from the FDA's MAUDE database over a ten-year period. They found 153 reports of bowel injuries, with a significant proportion requiring major surgical interventions, despite the presence of safety mechanisms designed to prevent such complications. The study highlights ongoing concerns regarding the safety of the NovaSure® device, particularly in relation to bowel and uterine injuries.

Evidence-Based Guidelines for Instrument and Handle Selection for Ergonomic Optimization in Laparoscopic Surgery

Apr 26, 2026

The authors aimed to develop evidence-based guidelines for ergonomic optimization in laparoscopic surgery by evaluating various instrument handle designs. Through a systematic review of the literature, they found that while some handle configurations may promote better wrist posture and reduce muscle activation, the evidence remains limited and inconsistent, with no definitive superiority among designs. They conclude that while conventional instruments are suitable for routine use, further research is needed to establish standardized ergonomic metrics for instrument development.

Artificial Intelligence in Minimally Invasive Gynecological Surgery: A Systematic Review of Task- Specific Performance and Clinical Translational Readiness

Apr 26, 2026

The authors aimed to systematically evaluate the task-specific performance and clinical readiness of artificial intelligence (AI) applications in minimally invasive gynecological surgery (MIGS) across preoperative, intraoperative, and postoperative phases. Their review identified that while AI models showed promising sensitivity and potential benefits in surgical planning, most studies had high risk of bias and limited external validation, indicating a need for multicenter prospective validation before routine clinical adoption.

Oral Gonadotropin-Releasing Hormone Antagonists for the Treatment of Endometriosis-Associated Pain: A Systematic Review and Meta-Analysis

Apr 23, 2026

The authors aimed to evaluate the efficacy of oral gonadotropin-releasing hormone (GnRH) antagonists compared to placebo in treating endometriosis-associated pain, specifically dysmenorrhea and non-menstrual pelvic pain. Their systematic review and meta-analysis of five phase 3 trials involving over 2,000 participants found that oral GnRH antagonists significantly reduced pain levels, with similar efficacy across different agents, supporting their use as effective second-line treatments for this condition.

Compartment-Specific Outcomes of Single-Mesh and Double-Mesh Reinforcement in Laparoscopic Sacrocolpopexy: A Retrospective Cohort Study

Apr 22, 2026

The authors aimed to compare the long-term outcomes of single-mesh versus double-mesh reinforcement in laparoscopic sacrocolpopexy, specifically focusing on compartment-specific failure and reoperation rates. Their findings indicated that while anatomical failure rates in the reinforced compartments were similar between the two groups, single-mesh reinforcement was associated with significantly higher risks of failure and reoperation in non-reinforced compartments, leading to worse overall outcomes without an increase in mesh-related complications.

Abdominal Wall Elevation for Pneumoperitoneum in Laparoscopic Gynecologic Surgery: A Retrospective Comparative Study of Experienced and Trainee Surgeons

Apr 21, 2026

The authors aimed to evaluate the success rate and complication incidence of pneumoperitoneum induction using an abdominal wall elevation device by surgeons with varying levels of experience in laparoscopic gynecologic surgery. The study found that both experienced surgeons and trainees achieved high success rates (100% and 95%, respectively) without major complications, indicating that the LevaLap 1.0 device is effective and safe for use by less experienced surgeons under supervision.