June 23, 2026 · American heart journal · DOI: 10.1016/j.ahj.2026.107520

DOAC Score Among Patients Receiving Vitamin K Antagonists

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This study investigates the effectiveness of the DOAC Score in assessing bleeding risk among patients with atrial fibrillation who are treated with vitamin K antagonists (VKAs). The authors found that the DOAC Score provided better risk stratification for major bleeding compared to the HAS-BLED score, demonstrating moderate discrimination in both clinical trial and registry settings. Overall, the findings suggest that the DOAC Score is a valuable tool for identifying patients at varying levels of bleeding risk while on VKAs.

Rahul Aggarwal, Christian T Ruff, Michael G Palazzolo, Fionn Cléirigh Büttner, Karen Pieper, John Eikelboom, Manesh Patel, Christopher B Granger, Lars Wallentin, Ziad Hijazi, Saverio Virdone, Peter Zimetbaum, Erick A Secemsky, Ajay K Kakkar, Robert P Giugliano, Robert W Yeh

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