The Association of Single Ventricle Morphology with Long Term Quality of Life Among Survivors: A Report from CHD PULSE (Congenital Heart Disease Project to Understand Lifelong Survivor Experience)

The authors aimed to investigate the association between single ventricle morphology and long-term quality of life, medical, neurocognitive, and socioeconomic outcomes in adults with congenital heart disease (CHD). Their study found no significant differences in outcomes between patients with left versus right ventricular morphology, but highlighted that single ventricle patients reported more medical comorbidities and lower educational attainment compared to their siblings, despite similar PROMIS scores in certain health domains. Overall, the findings suggest that while ventricular morphology does not impact long-term outcomes, significant disparities exist between SV patients and their siblings.