Hyponatremia: A Mechanistic Approach to Diagnosis and Management

The authors aim to address the challenges in diagnosing and managing hyponatremia by proposing a mechanistic approach that prioritizes understanding the primary abnormality of excess extracellular water over traditional volume categorization. By emphasizing the underlying pathophysiological mechanisms, the review seeks to enhance diagnostic and therapeutic strategies, ultimately improving patient care in cases of hyponatremia.